Don’t Be Left Behind. Keep Up With THE HERD!
Selected Highlighted News in the field of Autoimmune
Encephalitis December 2020 2nd edition
In this Issue~
- *Announcements: Shop & Support IAES, AE Awareness Month Shirts/New Arrivals at the AE Warrior Store
- *Children’s Corner: Effectiveness of Mycophenolate Mofetil in the Treatment of Pediatric Anti-NMDAR Encephalitis, Holiday Word Scramble Puzzles, Official Memo to Kris Kringle
- *Most Popular Image Downloads: User-friendly Chart – Understanding AE in the ICU, AE Infographic Poster
- *COVID-19’s Impact on the AE Community: Antibodies, Immunity & COVID-19, COVID-19 and the Brain: An Update, NMDA-receptor encephalitis Associated with COVID-19 infection in a toddler
- *Most Popular Visual: IAES’s Christmas List to Santa, So Few People Understandproduction
- *Featured AE Articles: Search for Viral Infections in Cerebrospinal Fluid From Patients With Autoimmune Encephalitis, LGI1 Antibody Encephalitis: Treatments and Long-term Outcome
- *Clinician’s Corner: Glucocorticoids: surprising new findings on their mechanisms of actions
- *COVID-19 Clinician’s Corner: FDA Takes Key Action in Fight Against COVID-19 By Issuing Emergency Use Authorization for First COVID-19 Vaccine, Fact Sheet contradictions/warnings
- *Open Access: Neurocritical care for Anti-NMDA receptor encephalitis
Ways to Shop & Support IAES
Have you wanted to support IAES, autoimmune encephalitis awareness, and the AE Warrior that you love?
Have you found our services helpful? Do you want to make sure patients are identified early and that they and their loved ones receive the best help possible during this difficult journey?
Here is an easy and affordable way to donate without feeling a thing when shopping with your Paypal account. Each time you check out you will be reminded that you can give $1 to IAES.
While shopping online via Amazon Smiles, you can support your favorite non-profit and get that great deal online!
Simply select IAES as the non-profit you want to support, and Amazon will donate 5% of our purchases to the International Autoimmune Encephalitis Society.
Here is a handy tool that will automatically redirect you to smile.amazon.com when you are shopping so you never have to worry about forgetting to type it in to ensure benefits go to IAES.
AE Warrior Store
Description: Autoimmune Encephalitis Awareness Month, February 2021 2-sided designs. May be ordered in Men’s, Women’s, and Children’s sizes in a variety of styles including a hoodie, long sleeve shirts, and colors.
Back reads: Autoimmune Encephalitis (AE): is a type of brain inflammation where the body’s immune system attacks healthy brain cells.
Spread awareness with these stylish shirts. Wearing this shirt may begin a conversation that could lead to saving a life. The proceeds of your purchase will immediately support autoimmune encephalitis patients, caregivers, and families who are walking this difficult journey. Proceeds also go to support research that may one day lead to a cure.
Other new arrivals are an AE Warrior What’s Your Superpower shirt with zebra art by Julia King and a pocket-sized password log.
Visit #AE Warrior Gifts on the IAES website for some great stocking stuffer ideas, many offerings there are free. Don’t forget to get a deck of AE Trivia Cards for your AE Warrior, family members, or your Neurologist.
Effectiveness of Mycophenolate Mofetil in the Treatment of Pediatric Anti-NMDAR Encephalitis: A Retrospective Analysis of 6 Cases
Results: Six children with anti-NMDAR encephalitis were treated with MMF in the 2nd or 3rd treatment disease event (3 cases vs. 3 cases). MMF initiation was mean 19.2 months (range 6–39 months) after disease onset at a mean dose of 25.6 mg/kg (range 19.6–28.4 mg/kg) for 14 months (range 6–26 months). Only two patients had transient mild diarrhea within 2 weeks of MMF application. During follow-up, one patient relapsed whilst on MMF, one patient discontinued MMF, and 4 cases were still on MMF.
Conclusion: The use of MMF in anti-NMDAR encephalitis may be effective and safe. MMF can be used as one of the relapse prevention options in patients who already have relapsed or possibly even after the first event. Delayed use may be the main reason for MMF failure.
Christmas Word Scramble puzzles for Cognitive Exercise and Rehabilitation
Official Memo To Santa
Most Popular Download
User-friendly Chart – Understanding AE in the ICU
AE Infographic Poster
COVID-19’s impact on the AE Community
Antibodies, Immunity, and COVID-19
NMDA-receptor encephalitis Associated with COVID-19 infection in a toddler
This case is by Dr. Michael Sweeney, a member of our medical advisory panel.
There have been two cases of anti-NMDAR encephalitis associated with SARS-CoV-2 in adults reported.
Both patients showed significant recovery following immunotherapy with steroids and IVIG. At the time of publication, the authors are unaware of other cases of anti-NMDAR encephalitis with recent SARS-CoV-2 infection in pediatric populations. As the understanding of both the neurological and non-neurological manifestations of SARS-CoV-2 in children are evolving, we report a child with SARS-CoV-2-associated anti-NMDAR encephalitis.
COVID-19 and the Brain: An Update
COVID-19 continues to spread around the world at an alarming rate. When we first wrote about neurologic complications from COVID-19 on June 30th, just under 10 million people had been infected globally. As of the writing of this post less than 5 months later, 12 million people have been infected in the United States alone, with over 58 million infections worldwide. Normally, one would not expect any major scientific advancements in 5 months on a single topic. These are not normal times, however, and the massive push to study this disease by scientists around the world has led to an outpouring of research on how SARS-CoV-2 might affect the brain. Here we will provide an update on what has been found and the big questions that still need to be answered.
Most Popular Visual~
IAES’s Christmas List to Santa
Featured AE Articles~
Search for Viral Infections in Cerebrospinal Fluid From Patients With Autoimmune Encephalitis
LGI1 Antibody Encephalitis: Treatments and Long-term Outcome
Glucocorticoids: surprising new findings on their mechanisms of actions
COVID-19 Clinician’s Corner
FDA Takes Key Action in Fight Against COVID-19 By Issuing Emergency Use Authorization for First COVID-19 Vaccine
Neurocritical care for Anti-NMDA receptor encephalitis
AE Trivia Playing Cards
The perfect companion for patients, Caregivers & Therapist
We appreciate the National Organization of Rare Diseases’ (NORD) enthusiastic support in recommending this groundbreaking product.
When you shop Amazon Smiles and select IAES as the non-profit you want to support, Amazon will donate 5% of our purchases to the International Autoimmune Encephalitis Society.
The need for our services has increased exponentially. This simple act of kindness, will support the work we do and advance our ability to service the community.
International Autoimmune Encephalitis Society is proud to be a platinum level participant on the Guide Star exchange, demonstrating or commitment to financial transparency. IAES is a charitable non-profit 501 (c)(3) organization. Tax ID#81-3752344
Donations raised are greatly appreciated and directly support research, patients, caregivers, and families through their journey so the best outcomes can be reached. Your contribution to our mission will help save a life and improve the quality of lives for others. Be a part of the solution by supporting IAES.
Driven by the knowledge that “Education is Power”, Int’l AE Society manages an educational support group for patients diagnosed with Autoimmune Encephalitis and their loved ones on Face Book, empowering them to be strong self-advocates and advocates that will lead them to best outcomes and recovery. We are the premiere organization leading in these vital roles.