
JULY NEWSLETTER
Selected Highlighted News in the field of Autoimmune
Encephalitis July 2018 1st edition
This issue includes ~ IAES has been nominated for the WEGO Health Awards 2018! Exciting Discovery of the Molecular Mechanism that causes anti-NMDAr encephalitis! Review of Immune-mediated disorders of the CNS in children from Doctor’s on our Doctor’s list. Listings of neurology patient support groups

IAES Nominated for WEGO Health Awards 2018
We at Int’l AE Society are proud and honored to be recognized for our advocacy and work in the Autoimmune Encephalitis Community. The categories we have been nominated for are:
Best in Show: Community
Best in Show: Facebook
Best Team Performance
Please share this and endorse our nomination. You can vote once in each category.

Exciting discovery in anti-NMDAr! A new study Directed by Dr. Dalmau, examines the molecular mechanisms that cause a type of autoimmune encephalitis: anti-NMDAr
Open Access article.
Study just released examines the mechanism that begins the disease process (parthenogenesis) of anti-NMDAr encephalitis. This will lead to Studies that will now focus on determining whether the antibodies of patients can alter other molecules that interact with NMDAR, in order to discover new potential therapeutic targets

Neuroimmune disorders of the central nervous system in children in the molecular era
Several doctors on the IAES Doctor’s list came together in this research. Immune-mediated disorders of the CNS in children are a complex group of demyelinating, inflammatory, parainfectious and postinfectious disorders with heterogeneous pathobiological mechanisms and clinical manifestations, often associated with fundamental derangement in immune regulation. In this Review, researchers aim to provide an update on their knowledge of neuroimmune disorders and highlight areas of research that are priorities for improving clinical management.
Beyond the limbic system: disruption and functional compensation of large-scale brain networks in patients with anti-LGI1 encephalitis
Conclusions Anti-LGI1 encephalitis is associated with a characteristic pattern of widespread functional network alterations. Increased DMN connectivity seems to represent a compensatory mechanism for memory impairment induced by hippocampal damage. Network analyses may provide a key to the understanding of clinical symptoms in autoimmune encephalitis and reveal changes of brain function beyond apparent structural damage.

International Autoimmune Encephalitis Society (IAES) is a Family/Patient centered organization that assists members from getting a diagnosis through to recovery and the many challenges experienced in their journey.
Driven by the knowledge that “Education is Power”, Int’l AE Society manages an educational support group for patients diagnosed with Autoimmune Encephalitis and their loved ones on Face Book, empowering them to be strong self-advocates and advocates that will lead them to best outcomes and recovery. We are the premiere organization leading in these vital roles.
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