Selected Highlighted News in the field of Autoimmune
Encephalitis November 2018 1st edition
In this Issue: Mayo Clinic develops new testing for MOG and ApQ4 antibodies and discovered two new antibodies in 2017 – GFAP and MAP1b. Slideshow presentation of Drs. Graus and Dalmau’s recent overview of AE- A ‘must’/’go to’ resource. Updated information on Autoimmune Epilepsy including reference chart. The Lancet Summit November 15-18th Barcelona, Spain
Mayo Clinic Develops New Testing for antibodies in
MOG and AQP4
Mayo Clinic now offers a comprehensive central nervous system demyelinating disease evaluation that includes both MOG antibody (the first-in-the-U.S. test to detect antibodies to the MOG protein) and AQP4 antibody tests. Mayo studies indicate MOG disease is twice as common as AQP4- IgG-associated diseases and affects about 1 million people. There is no overlap between the two antibodies in an individual patient. The combination of the two tests—AQP4 and MOG antibodies—allows for the most comprehensive evaluation for patients recently diagnosed with demyelinating diseases.
In 2017, Mayo discovered 2 new new biomarkers for Autoimmune Encephalitis: GFAP and MAP1b antibodies
GET YOUR LEARNING ON! IAES believes this Research will be One of the Most Highly Cited by Neurologists in the Field
IAES wants all of our members to better understand antibody-mediated Autoimmune Encephalitis so you become stronger advocates and self- advocates. Education is Power! It helps you reach recovery and your best possible outcomes.
We highly suggest you spend time with Dr. Graus and Dr. Dalmau and view this OUTSTANDING slide show that reviews their recently published work from March 2018 in the New England Journal of Medicine.
You have heard us discuss Autoimmune Epilepsy since Mayo Clinic developed an Epilepsy Autoimmune Evaluation in 2014. For an epilepsy to meet this classification, evidence of autoimmune-mediated central nervous system (CNS) inflammation is required. Treatment of immunologic epilepsy includes targeted immunotherapies in combination with antiepileptic drugs. These are the same antibodies in AE (see referenced chart above). This article seeks to provide a basic clinical approach to diagnosis and treatment.
The Lancet Summit: Inflammation and Immunity in Disorders of the Brain and Mind
November 15-17, 2018
International Autoimmune Encephalitis Society (IAES) is a Family/Patient centered organization that assists members from getting a diagnosis through to recovery and the many challenges experienced in their journey.
Driven by the knowledge that “Education is Power”, International Autoimmune Encephalitis Society manages an educational support group for patients diagnosed with Autoimmune Encephalitis and their loved ones, empowering them to be strong self-advocates and advocates that will lead them to best outcomes and recovery. We are the premiere organization leading in these vital roles. Raising awareness of Autoimmune Encephalitis across the many specialties of medicine that come in contact with these disorders and with the general public to ensure a timely and accurate diagnosis resulting in an aggressive treatment plan for best outcomes.
“Empowering victims of Autoimmune Encephalitis and their caregivers through Support and Education”.